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目的:探讨江苏盐城地区不同年龄宫颈癌及癌前病变患者的血液检查、临床特征和治疗情况等,以便正确了解宫颈癌及癌前病变的临床特征及规律。方法:对2011~2013年住院的260例宫颈癌及癌前病变患者的临床资料进行回顾性分析,根据年龄分为≤45岁组和>45岁年龄组。结果:≤45岁组的宫颈癌及癌前病变患者临床症状以接触性出血为主,而>45岁组临床症状以阴道不规则流血为主;≤45岁组临床分期以癌前病变和宫颈癌0~Ⅰ期为主,所占比例分别为43.2%和32.8%,>45岁组临床分期以宫颈癌Ⅱ期为主,占56.1%;两组组织病理学类型及分级、淋巴转移之间比较,差异无统计学意义(P>0.05);≤45岁组患者单纯手术治疗为主,且保留卵巢功能所占比例较高,而>45岁组患者以手术结合放、化疗辅助治疗为主,且以广泛全子宫双附件切除和盆腔淋巴结清扫术所占比例较高。结论:正确了解不同年龄宫颈癌及癌前病变患者临床特征及其规律,对提高早期诊断和改善预后有重要意义。
Objective: To investigate the blood tests, clinical features and treatment of patients with cervical cancer and precancerous lesions of different ages in Yancheng, Jiangsu Province in order to correctly understand the clinical features and laws of cervical cancer and precancerous lesions. Methods: The clinical data of 260 cases of cervical cancer and precancerous lesions hospitalized from 2011 to 2013 were retrospectively analyzed. According to the age, the patients were divided into the group of 45 years old and 45 years old. Results: The clinical symptoms of cervical cancer and precancerous lesions in 45-year-old group were mainly contact bleeding, while the clinical symptoms in> 45-year-old group were mainly vaginal irregular bleeding. The clinical stage of ≤45-year-old group was related to precancerous lesions and cervical The cancers were stage 0 to stage Ⅰ with the proportions of 43.2% and 32.8% respectively. The clinical stage of> 45 years old group was mainly cervical cancer stage Ⅱ, accounting for 56.1%. The histopathological types, grading and lymphatic metastasis The difference was not statistically significant (P> 0.05). The patients under 45 years of age were treated by surgery only, and the proportion of retained ovarian function was higher, while patients over 45 years of age were treated by surgery combined with adjuvant chemotherapy , And to a wide range of uterine double attachment resection and pelvic lymphadenectomy accounted for a higher proportion. Conclusion: Correct understanding of different ages of cervical cancer and precancerous lesions in patients with clinical features and their rules, to improve early diagnosis and improve prognosis of great significance.