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目的 观察复合生长因子治疗创伤性溃疡的临床效果。方法 将 17例正颌外科患者术后的双侧创伤性口角溃疡随机分成用药侧和对照侧。用药侧创面涂擦复合生长因子 ,对照侧涂擦生理盐水。应用开放型质反应双向序贯实验法进行疗效评价。结果 当实验观察到第 17例时 ,结果显示复合生长因子促创面愈合作用优于生理盐水。所有创面都能愈合 ,用药创面与对照创面愈合的差异主要在于愈合时间 ,用药创面愈合均在 1周之内 ,而对照创面 1周内愈合的仅 3例 ,其余为 10～ 12d。结论 局部应用复合生长因子是加速创伤性溃疡愈合的有效措施。
Objective To observe the clinical effect of composite growth factor in the treatment of traumatic ulcer. Methods Seventeen patients with orthognathic surgery underwent bilateral traumatic mouth ulcers randomly divided into medication side and control side. Drug side wound rub compound growth factor, control side rubbed saline. Application of open-type two-way sequential response qualitative response evaluation. Results When the 17th experiment was observed, the results showed that the composite growth factor promoted wound healing better than saline. All the wounds healed. The difference between healing wounds and control wound healing mainly lies in the healing time. The healing wounds of the wounds were all within 1 week, whereas in the control wounds, only 3 wounds healed in one week and the rest from 10 to 12 days. Conclusion Local application of composite growth factor is an effective measure to accelerate the healing of traumatic ulcer.