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目的 观察前列腺素E1治疗病毒性肝炎高胆红素血症的疗效。方法 2 35例病毒性肝炎高胆红素血症病人随机分为治疗组 12 0例 ,对照组 115例。两组均采用相同的基础疗法。治疗组加用前列腺素E12 0 0 μg加入 10 %葡萄糖5 0 0ml中 ,缓慢静脉滴注 ,每天 1次。疗程 4周或TBil正常后停用。结果 治疗组总有效率为 89.2 % ,对照组为 73 %。两组相比差异有显著性意义 (P <0 .0 5 )。治疗组在降酶、退黄及缩短肝功能复常时间方面明显优于对照组 (P <0 .0 1)。结论 前列腺素E1治疗病毒性肝炎高胆红素血症疗效确切 ,适合各级医院应用
Objective To observe the efficacy of prostaglandin E1 in the treatment of viral hepatitis with hyperbilirubinemia. Method 2 35 patients with viral hepatitis with hyperbilirubinemia were randomly divided into treatment group of 120 cases, control group of 115 cases. Both groups used the same basic therapy. The treatment group with prostaglandin E12 0 0 μg added 10% glucose 500 ml, slow intravenous infusion, once daily. After 4 weeks of treatment or normal TBil disabled. Results The total effective rate was 89.2% in the treatment group and 73% in the control group. There was significant difference between the two groups (P <0.05). The treatment group was significantly better than the control group in reducing the enzyme, yellowing and shortening the time of recovery of liver function (P <0.01). Conclusions Prostaglandin E1 is effective in treating viral hepatitis with hyperbilirubinemia and is suitable for all levels of hospital