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目前,国内文献报道的风疹疫苗免疫学效果观察采用的检测方法多为血凝抑制试验(HI)〔1,2〕,由于检测的HI抗体包含IgG和IgM抗体,而在机体抗微生物免疫中起主要作用的血清球蛋白是IgG。因此,检测其免后特异性IgG抗体滴度,对疫苗的免疫原性考核或效果观
At present, most of the detection methods used in the observation of the immunological effects of rubella vaccine reported in the domestic literature are the hemagglutination inhibition test (HI) [1, 2]. Since the tested HI antibody contains IgG and IgM antibodies, the anti-microbial immunity The major role of serum globulin is IgG. Therefore, to test its post-immune-specific IgG antibody titers, immunogenicity assessment or effect of the vaccine