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目的老年高血压是动脉粥样硬化形成的因素之一。老年高血压具有脉压差大的特点。本文探讨脉压差与老年高血压患者动脉粥样硬化形成的关系。方法以98例老年高血压患者为对象,按24h平均脉压差大小分为<60mm Hg、60～69mm Hg和≥70mm Hg三组。用彩色多普勒超声检查颈动脉粥样硬化斑块及最大内膜中层厚度(IMT)。对比分析脉压差大小与颈动脉粥样硬化斑块发生率和IMT之间关系。结果本研究结果显示,随着脉压差的逐渐加大,老年高血压病人的颈动脉最大内膜中层厚度逐渐增加,颈动脉粥样硬化斑块发生率也跟着逐渐增高。结论脉压差增大可促进动脉粥样硬化斑块的形成和发展。脉压差是老年高血压病人动脉硬化的良好预测因子之一。
Aged hypertension is one of the factors of atherosclerosis. Elderly hypertension has the characteristics of large pulse pressure difference. This article discusses the relationship between pulse pressure and atherosclerosis in elderly patients with hypertension. Methods A total of 98 cases of elderly hypertensive patients were divided into three groups according to the average 24h pulse pressure difference of <60mm Hg, 60 ~ 69mm Hg and ≥70mm Hg. Carotid artery atherosclerotic plaque and maximal intima-media thickness (IMT) were examined by color Doppler sonography. The relationship between pulse pressure difference and carotid atherosclerosis plaque incidence and IMT was analyzed. Results The results showed that with the gradual increase of pulse pressure, the intima-media thickness of the carotid artery in elderly hypertensive patients gradually increased, and the incidence of carotid atherosclerotic plaque gradually increased. Conclusion Increased pulse pressure can promote the formation and development of atherosclerotic plaque. Pulse pressure is one of the good predictors of atherosclerosis in elderly hypertensive patients.