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作者从所见的16例属于由Jadassohn及由Schweninger等所描述的皮肤松弛症的斑萎缩患者,提出本病可能是一种伴有临床或至少具有组织病理学炎症的慢性破坏性病变。为此,对其中5例有典型临床皮损的活检标本的冰冻切片,用抗Leu—1、Leu—2a、Leu—3、HLA—DR、OKM1和OKT6单克隆抗体进行了研究,以期更好地了解损害内炎性浸润的单一核细胞的构成情况。结果发现所有的活检标本均显示炎症细胞浸润,其中血管周围浸润的细胞,20～30%与属于全T细胞的抗Leu 1单克
The authors, from the 16 patients with plaque atrophy that were seen to belong to dermatophytosis described by Jadassohn and Schweninger et al., Suggested that the disease may be a chronic, devastating disease with clinical or at least histopathological inflammation. To this end, frozen sections of 5 biopsies with typical clinical lesions were studied using anti-Leu-1, Leu-2a, Leu-3, HLA-DR, OKM1 and OKT6 monoclonal antibodies in order to better To understand the damage infiltrating infiltration of mononuclear cells in the composition. As a result, it was found that all the biopsy specimens showed inflammatory cell infiltration with infiltration of perivascular cells by 20 to 30% with anti-Leu 1 monoclonal