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目的探讨白血病患者血清甲状腺素水平变化及对预后的影响。方法应用放射免疫分析法对76例白血病患者和40例正常人进行甲状腺功能检测,并对其与临床的关系进行分析。结果白血病患者血清甲状腺素水平降低,非甲状腺疾病综合征发生率高(57/76例),且与疾病的进展和恶化有关。结论动态检测甲状腺素水平能反映白血病患者的全身状态和评估预后。
Objective To investigate the changes of serum thyroxine level in patients with leukemia and its prognosis. Methods Radioimmunoassay was used to detect thyroid function in 76 patients with leukemia and 40 normal controls, and their relationship with clinical status was analyzed. Results Serum thyroxine level was decreased in patients with leukemia, and the incidence of non-thyroid disease syndrome was high (57/76 cases), which was related to the progress and deterioration of the disease. Conclusions The dynamic detection of thyroxine can reflect the general status of patients with leukemia and evaluate the prognosis.