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观察东莨菪碱（ｓｃｏｐｏｌａｍｉｅ，Ｓｃｏｐ）对大鼠下丘脑旁室核精氨酸升压素的影响。方法以不同浓度Ｓｃｏｐ推挽灌流大鼠下丘脑室旁核（ｐａｒａｖｅｎｔｒｉｃｕｌａｒｎｕｃｌｅｕｓ，ＰＶＮ）。结果挽出液中精氨酸升压素（ａｒｇｉｎｉｎｅ－ｖａｓｏｐｒｅｓｓｉｎ，ＡＶＰ）含量随推挽时间延长而增多。结论Ｓｃｏｐ可促进ＰＶＮ释放内源性ＡＶＰ，这对了解Ｓｃｏｐ抗休克的机理有重大的意义。
To observe the effects of scopolamine (Scopolamie, Scop) on arginine vasopressin in hypothalamic nucleus of rats. Methods The hypothalamic paraventricular nucleus (PVN) was induced by different concentrations of Scop in rats. Results The content of arginine-vasopressin (AVP) in pull-out fluid increased with the push-pull time. Conclusion Scop can promote PVN release of endogenous AVP, which is of great significance to understand the mechanism of Scop anti-shock.