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目的观察米非司酮配伍米索前列醇终止49天内妊娠的临床效果,分析影响药物流产成功的因素。方法将2308例无药流禁忌证、B超确诊宫内妊娠、停经≤49天、年龄20~40岁、本人自愿要求药物终止妊娠的健康育龄妇女,按顿服法或分次服药法服米非司酮150mg,米索前列醇600μg。结果完全流产率86.35%。影响药流成功的因素包括孕龄、年龄、既往分娩史、孕产次等多种因素。结论米非司酮配伍米索前列醇是一种安全、简便、有效的终止早孕的方法,但一定要掌握好适应证,注意影响药流成功的各种因素。
Objective To observe the clinical effect of mifepristone combined with misoprostol on termination of pregnancy within 49 days and analyze the factors affecting the success of medical abortion. Methods 2308 cases of drug-free flow contraindications, B-diagnosed intrauterine pregnancy, menopause ≤ 49 days, aged 20 to 40 years, I voluntarily require termination of pregnancy healthy women of childbearing age, according to Dayton service or sub-medication to take the law Ketones 150mg, misoprostol 600μg. Results Complete abortion rate of 86.35%. Factors affecting the success of medical abortion include gestational age, age, past history of delivery, pregnancy and other factors. Conclusion Mifepristone combined with misoprostol is a safe, simple and effective method of termination of early pregnancy, but we must grasp the indications, pay attention to the various factors that affect the success of medical abortion.