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本期刊登了一篇“药物治疗的获益与损害:观察性研究与随机试验应相互补充”的论述性文章(见本期第5页)。《英国医学杂志》(BMJ)曾刊登过几篇关于不同药物治疗利弊的类似文章。实际上提出一个“如何全面、正确地评价药物”的问题。药物治疗的目的是为了减少病人的痛苦、提高人群的健康水平、造福社会。全面评价一种药物,首先应考虑是否安全(无或很少有不良反应)、有效,病人长期使用是否可以耐受,价格是否低廉(符合成本-效益),以及是否有利于病人的劳动能力和生活质量的提高。
This issue of an article entitled “Benefits and harm of drug treatment: observational studies and randomized trials should complement each other” (see page 5 of this issue). The British Medical Journal (BMJ) has published several articles on the pros and cons of different medical treatments. In fact, put forward a “how to comprehensively and correctly evaluate the drug” issue. The purpose of medical treatment is to reduce the patient’s suffering and improve the health of the population for the benefit of society. A comprehensive assessment of a drug should first consider whether it is safe (with or without adverse reactions), effective, long-term patient tolerability, inexpensive (cost-effective), and beneficial to the patient’s ability to work and Improve the quality of life.