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目的分析并探讨抗菌药物的不合理用药现状,为制定相应对策提供参考。方法对所抽查的全部处方以及相关资料进行分类整理,主要对抗菌药物处方的选用、给药方案、用法用量、联合用药、药理拮抗等情况进行分类统计。结果本组研究共抽查覆盖各个科室的处方6290张,其中有2140张处方为抗菌药物处方,占总抽查数的34.02%。对2140张抗菌药物处方进行检查发现不合理用药处方共有584张,占27.29%,并且一部分抗菌药物不合理处方中有多项不合理用药情况。对不合理用药情况进行分析表明不合理用药类别主要为:选择不合理、给药方案不合理、重复给药、无指征滥用、理化禁忌、毒性相加以及药理拮抗等。结论医院药剂科必须对门诊处方以及住院处方进行严格检查与监督,并制定有效的管理制度及措施,定期组织开展抗菌药物用药知识的相关培训,及时纠正抗菌药物的不合理用药现象,提高抗菌药物的合理用药水平及医疗质量。
Objective To analyze and discuss the status of irrational use of antimicrobial agents and provide reference for making corresponding countermeasures. Methods All the prescriptions and relevant data were sorted and sorted out. The main prescriptions for antibacterial drugs, dosing regimen, dosage, combination therapy and pharmacological antagonism were classified. Results A total of 6290 prescriptions covering all departments were included in this study. Among them, 2140 prescriptions were prescribed antibiotics, accounting for 34.02% of the total number of spot checks. An examination of 2140 prescriptions for antimicrobial agents found that there were 584 unreasonable prescriptions, accounting for 27.29%, and there were a number of unreasonable prescriptions used in part of the unreasonable prescriptions of antimicrobial agents. Analysis of irrational drug use shows that the main types of irrational drug use are: unreasonable choice, unreasonable dosing regimen, repeated dosing, no indication of abuse, physical and chemical taboo, toxicity addition and pharmacological antagonism. Conclusion The pharmacy department of the hospital must strictly inspect and supervise outpatient prescriptions and inpatient prescriptions and formulate effective management rules and measures. Regularly organize relevant training on the knowledge of antimicrobial drug use, correct the irrational drug use of antimicrobial drugs in time and improve the antimicrobial drug The rational use of medicine and medical quality.