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目的 探讨９９Ｔｃｍ双半胱乙酯（ＥＣＤ）脑血流灌注显像评价脑肿瘤术牵拉伤局部脑血流量（ｒＣＢＦ） 改变的价值。方法 对２１ 例脑肿瘤病人手术前后进行脑血流灌注断层显像，测量ｒＣＢＦ减低区范围，半定量法比较和分析术前肿瘤周围皮层及术后牵拉区ｒＣＢＦ的改变。对术后牵拉伤ｒＣＢＦ减低区分为内、外侧，并测定半定量值。结果 手术前肿瘤周边区及术后牵拉区均见缺血性改变，手术前后ｒＣＢＦ减低区域和术前瘤周、术后牵拉区ｒＣＢＦ半定量值差异有显著性（Ｐ＜ ０－０１）。牵拉外侧缘至牵拉区中心ｒＣＢＦ逐渐降低，牵拉区内外侧间缺血程度差异有显著性（ Ｐ＜ ０－００１），内侧大于外侧。术后一过性偏瘫病人随症状好转而缺血改善。结论 ９９ＴｃｍＥＣＤ脑血流灌注显像是评价脑肿瘤术后牵拉伤及ｒＣＢＦ改变的有效方法
Objective To investigate the value of 99Tcmbidocysteine (ECD) cerebral perfusion imaging in assessing the changes of regional cerebral blood flow (rCBF) after traumatic brain injury in brain tumors. Methods Cerebral perfusion tomography was performed in 21 patients with brain tumor before and after operation. The extent of rCBF reduction was measured. The changes of rCBF in the peri-cortex and postoperative traction area were compared and analyzed by semi-quantitative method. The reduction of rCBF after traumatic injury was divided into medial and lateral, and the semi-quantitative values were measured. Results Before operation, the ischemic changes were found in the peripheral area of the tumor and in the area of postoperative traction. There was a significant difference in the rCBF semiquantitative value between the area of rCBF reduction before and after surgery and the area around the tumor before and after operation (P <0-01) . The rCBF was gradually decreased from the lateral margin to the center of the distraction region, and there was significant difference between the lateral and lateral extents of the distraction region (P <0-001). Postoperative transient hemiplegia patients with ischemic improvement improved with symptoms. Conclusion 99Tcm ECD cerebral perfusion imaging is an effective method to evaluate the changes of rCBF after traumatic brain injury