论文部分内容阅读
患者女,31岁。躯干及四肢出现结节性红斑伴发热8个月,泛发并加重2个月。皮损组织病理示:皮下脂肪组织坏死伴较多淋巴细胞浸润,真皮深部血管周围及皮肤附属器周围较多淋巴细胞浸润,细胞欠规则,以小淋巴细胞及中等大小淋巴细胞为主;骨穿示:骨髓增生活跃,粒系占43.0%,红系占42.5%。可见组织细胞有吞噬现象,周围血见幼粒细胞。诊断:皮下脂膜炎样T细胞淋巴瘤;噬血细胞综合征。
Female patient, 31 years old. Nodular erythema appeared in the trunk and limbs with fever for 8 months, generalized and aggravated for 2 months. Pathological lesions showed: subcutaneous adipose tissue necrosis with more infiltration of lymphocytes, dermal deep perivascular and skin appendages around more lymphocytes infiltration, cells less regular, with small lymphocytes and medium-sized lymphocytes; bone through Show: Active bone marrow hyperplasia, granulocyte accounted for 43.0%, erythroid accounted for 42.5%. Visible tissue cells phagocytosis, peripheral blood see promyelocytic. Diagnosis: subcutaneous panniculitis-like T-cell lymphoma; hemophagocytic syndrome.