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本文报道我科近10年来收治的继发性纯红再障15例,作者认为药物、感染、其他血液疾病及食松树嫩芽等可能为诱发因素。本组的临床表现为起病急(60%)、贫血症状(100%)、轻度肝脾肿大(27%)、浅表淋巴结肿大(20%)、皮肤有少许出血点(20%)。治疗原则是根治原发病和去除诱发因素。本组15例无死亡者,13例随访16月～8年半均无复发。本病的临床特点:(1)发病年龄多数是2岁以上;(2)无家族史,不伴先天畸形;(3)有明确的原发病或诱发因素;(4)呈自限性;(5)可伴白细胞和血小板减少;(6)治疗反应好,预后佳,无复发。先天性纯红再障与继发性纯红再障的不同处在于前者发病年龄小、预后较差。
This article reports 15 cases of secondary pure red aplastic anemia treated in our department in recent 10 years. The authors believe that drugs, infections, other blood diseases and sprouting of pine needles may be the predisposing factors. The clinical manifestations of this group were acute onset (60%), anemia (100%), mild hepatosplenomegaly (27%), superficial lymph nodes (20%), ). The principle of treatment is to cure the primary disease and remove the predisposing factors. The group of 15 patients without death, 13 cases were followed up for 16 months to 8 years and no recurrence. The clinical features of the disease: (1) the age of onset is mostly older than 2 years; (2) no family history without congenital anomalies; (3) a clear primary disease or predisposing factors; (4) self-limiting; (5) may be associated with leukopenia and thrombocytopenia; (6) good response to treatment, good prognosis, no recurrence. Congenital pure red aplasia and secondary pure red aplastic anemia is that the former age of onset is small, the prognosis is poor.