Spatio-temporal Expression Study of Phosphorylated 70-kDa Ribosomal S6 Kinase （p70S6k） in Mesial Tem

• 作 者: Xiao-liang Xing Long-ze Sha Yu
• 机 构: NationalLaboratoryofMedicalMolecularBiology,DepartmentofNeurology
• 出 处: 中国医学科学杂志：英文版
• 发表日期: 2012年1期
• 关键词: 时空表达 癫痫 颞叶 核糖体 磷酸化 小鼠模型 激酶 细胞免疫反应 mesial temporal lobe epilepsy p70S6k kainate
• 基金项目: Supported by National Natural Science Foundation of China （31021091, 30971001）, Beijing Natural Science Foundation （7102109）, and Fok Ying Tong Education Foundation （121024）.

Objective To determine the spatio-temporal expression of p70S6k activation in hippocampus in mesial temporal lobe epilepsy. Methods Temporal lobe epilepsy model was established by stereotaxically unilateral and intrahip-pocampal injection of kainite acid