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1955年,印度新德里因城市供水受粪便污染,29000人发生肝炎,数十年后经回顾性诊断,证实为首次戊型肝炎(HE)暴发。非洲、原苏联中亚地区的共和国、阿富汗、孟加拉、婆罗洲、缅甸、中国、印度、墨西哥、蒙古、尼泊尔、巴基斯坦和一些中东国家也曾报告 HE 的暴发。暴发的病例数估计为<100～29000。最近,来自苏丹、埃塞俄比亚和埃及的报道,提示戊型肝炎病毒(HEV)感染可能占这些国家成人和儿童急性散发性肝炎的很大部分。近年证实墨西哥人群中有 HEV 感染,提示 HEV 感染的传播可能比想象的更广泛,特别在美国-墨西哥边境。1989～1992年,6名参加国际旅游的美国人,被确认
In 1955, the city of New Delhi, India, was contaminated with manure due to water supply in the city. Thirty-nine thousand people developed hepatitis and, after decades of retrospective diagnosis, was confirmed as the first outbreak of hepatitis E (HE). The outbreaks of HE have also been reported in Africa, the former Soviet Central Asian republics, Afghanistan, Bangladesh, Borneo, Myanmar, China, India, Mexico, Mongolia, Nepal, Pakistan and some Middle East countries. The number of outbreaks is estimated at <100-29,000. Recent reports from the Sudan, Ethiopia and Egypt suggest that hepatitis E virus (HEV) infection may account for a large proportion of acute fulminant hepatitis in adults and children in these countries. In recent years, HEV infection has been confirmed in Mexico’s population, suggesting that the spread of HEV infection may be more widespread than expected, especially on the U.S.-Mexican border. From 1989 to 1992, six Americans participating in international tourism were confirmed