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目的观察碳酸氢钠治疗口腔真菌感染(呼吸机治疗引发)的临床效果,总结其应用价值。方法选取2011年6月至2013年1月呼吸机治疗引发口腔真菌感染的患者50例,按信封法随机分成两组,应用碳酸氢钠治疗为试验组,应用制霉素治疗为对照组,统计两组治疗效果。结果试验组pH值、真菌感染持续时间、总住院时间分别为(6.7±0.6)、(7.6±1.9)d、(16.5±4.1)d,以上观察指标均优于对照组,此外,试验组不良反应发生率16.0%低于对照组32.0%,差异具有统计意义(P<0.05)。结论碳酸氢钠治疗呼吸机治疗引发的口腔真菌感染,效果显著,值得推广。
Objective To observe the clinical effect of sodium bicarbonate in the treatment of oral fungal infection (induced by ventilator therapy), and to summarize its clinical value. Methods From June 2011 to January 2013, 50 patients with oral fungal infection caused by ventilator were randomly divided into two groups according to the envelope method. Sodium bicarbonate was used as the experimental group, and the nystatin was used as the control group. Statistics Two groups of treatment. Results The pH value, duration of fungal infection and total hospital stay were (6.7 ± 0.6), (7.6 ± 1.9) days and (16.5 ± 4.1) days, respectively. The above indexes were better than the control group. In addition, The response rate was 16.0% lower than that of the control group (32.0%), the difference was statistically significant (P <0.05). Conclusion Sodium bicarbonate treatment of oral machine caused by oral fungal infection, the effect is significant, it is worth promoting.