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目的 比较早产儿与足月儿坏死性小肠结肠炎 (necrotizingenterocolitis ,NEC)临床特点。 方法 回顾性分析 1994至 2 0 0 3年我所收治的早产NEC患儿 2 8例和足月NEC患儿 3 5例的临床表现、X线表现和实验室检查特点。 结果 早产儿组与足月儿组比较皮肤灰白 5 4% (15 / 2 8)和 2 6% (9/ 3 5 ) ,P <0 .0 5 )、肌张力低下 [4 6% (13 / 2 8)和 14 % (5 / 3 5 ) ,P <0 .0 1]等全身表现明显 ;肠鸣音减弱或消失比足月儿组多见 [5 7% (16/ 2 8)与 2 3 % (8/ 3 5 ) ,P <0 .0 1] ;代谢性酸中毒 [5 4% (15 / 2 8)和 2 3 % (8/ 3 5 ) ,P <0 .0 5 ]和血清尿素氮增高 [3 6% (10 / 2 8)和 14 % (5 / 3 5 ) ,P <0 .0 5 ]比例高。 结论 早产儿NEC病情严重 ,进展迅速 ,应该给予及时正确的处理。并对发病趋势、发病日龄、早期诊断和手术治疗进行了讨论。
Objective To compare the clinical features of neonatal necrotizing enterocolitis (NEC) with premature infants. Methods The clinical features, X-ray findings and laboratory features of 28 cases of preterm NEC and 35 cases of term NEC were retrospectively analyzed from 1994 to 2003. Results Compared with full-term infants, premature infants showed a significant reduction in skin tone (44%, 15/28 and 26%, P <0.05, respectively) 2) and 14% (5/35), P <0. 01]. The bowel sounds weakened or disappeared more than those in term infants [57% (16/2 8) vs. 2 Metabolic acidosis [5 4% (15/28) and 23% (8/3 5), P <0 05], and 3% (8/3 5), P 0 01; Serum urea nitrogen increased [36 (10/28) and 14% (5/35), P <0 05] a high proportion. Conclusions NEC in preterm infants is severely exacerbated and promptly treated. NECs should be treated timely and correctly. The incidence of disease, the age of onset, early diagnosis and surgical treatment were discussed.