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前列腺癌骨转移的发生率很高。目前，全身骨扫描是诊断和监测前列腺癌患者骨转移的金标准，但骨扫描有其局限性。采用放免法检测的血清ＰＩＣＰ和ＩＣＴＰ是诊断骨骼病变的较好的生化指标，可用于监测前列腺癌患者的骨转移情况以及评价治疗效果。
The incidence of prostate cancer bone metastases is high. At present, the whole body bone scan is the gold standard for diagnosis and monitoring of bone metastases in patients with prostate cancer, but the bone scan has its limitations. Serum PICP and ICTP detected by radioimmunoassay are good biochemical markers for the diagnosis of bone diseases. They can be used to monitor the bone metastasis and evaluate the therapeutic effect in patients with prostate cancer.