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尿中β_2-微球蛋白(β_2-m)、白蛋白(Alb)、免疫球蛋白-G(IgG)及血中β_2-m的联合测定对肾脏损害部位和程度的诊断有重要意义。高血压病是临床常见病和多发病,且病程长,而产生多种并发症,特别是心、脑、肾尤为明显。有关高血压病人的尿β_2-m、Alb、IgG及血β_2-m水平的综合分析不多。为进一步了解高血压病人上述指标的改变情况,我们作了如下探讨。材料和方法一、对照组:选健康人32例(男19例,女13例)年龄20～26岁,均无肝、肾及高血压等疾病,尿蛋白定性为阴性,尿沉渣检查无异常。二、高血压病组:40例(男31例,女9例)年龄24～73岁。其中高血压病Ⅰ型11例;高血压病Ⅱ期29例。
The combined determination of urinary β_2-microglobulin (Alb), albumin (Alb), immunoglobulin-G (IgG) and β_2-m in blood is of great significance for the diagnosis of the location and extent of renal damage. Hypertension is a common clinical disease and frequently-occurring disease, and the longer duration, and produce a variety of complications, especially the heart, brain, kidney is particularly evident. A comprehensive analysis of urinary β_2-m, Alb, IgG and β_2-m levels in patients with hypertension is rare. To further understand the changes in the above indicators of hypertension patients, we made the following discussion. Materials and Methods First, the control group: 32 healthy subjects (19 males and 13 females) were selected and aged 20 to 26 years old without any diseases such as liver, kidney and high blood pressure. Urine protein was qualitatively negative and urinary sediment examination was normal . Second, hypertension group: 40 cases (31 males and 9 females) aged 24 to 73 years. Among them, 11 cases of hypertension type Ⅰ and 29 cases of hypertension Ⅱ phase.