Induction of Apoptosis by Recombinant Soluble Human TRAIL in Jurkat Cells

• 作 者: GEN-HONG YAO LI-JUN LING JIAN-
• 机 构: DepartmentofTransfusion,MedicalSchool
• 出 处: 生物医学与环境科学：英文版
• 发表日期: 2007年6期
• 关键词: 细胞凋亡 轨迹 JURKAT细胞 细胞激活机 TRAIL Apoptosis Jurkat cells
• 基金项目: This research was supported by Jiangsu Projects for Postdoctoral Research Funds （No. 0601025B） and National Projects for Postdoctoral Research Funds （No. 20060390940）.ACKNOWLEDGEMENTSThe authors thank

Objective To investigate the therapeutic potential of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, and to analyze TRAIL-induced apoptosis in Jurkat cells. Methods Expression of TRAIL receptors (DR