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目的探讨射频消融术联合肝动脉内化疗栓塞治疗肝癌的临床疗效。方法选取临汾市人民医院2013年收治的原发性肝癌患者80例,按照随机双盲法分为对照组与研究组,各40例。对照组予以经肝动脉内化疗栓塞治疗,研究组在对照组基础上予以射频消融术治疗,比较两组患者临床疗效、复发率及术后1年、3年生存率及生存期。结果研究组总有效率高于对照组,总复发率低于对照组(P<0.05)。两组患者1年生存率比较,差异无统计学意义(P>0.05);研究组3年生存率高于对照组,生存期长于对照组(P<0.05)。结论射频消融术联合肝动脉内化疗栓塞治疗肝癌的临床疗效确切,远期效果好。
Objective To investigate the clinical efficacy of radiofrequency ablation combined with intrahepatic arterial chemoembolization in the treatment of liver cancer. Methods Totally 80 patients with primary liver cancer admitted to Linfen People’s Hospital in 2013 were divided into control group and study group according to randomized double-blind method, 40 cases in each group. The control group was treated with intrahepatic arterial chemoembolization. The study group was treated with radiofrequency catheter ablation on the basis of the control group. The clinical efficacy, recurrence rate and 1 year, 3 year survival rate and survival time were compared between the two groups. Results The total effective rate of study group was higher than that of control group, and the total recurrence rate was lower than that of control group (P <0.05). There was no significant difference in one-year survival rate between the two groups (P> 0.05). The 3-year survival rate of the study group was higher than that of the control group, and the survival rate was longer than that of the control group (P <0.05). Conclusion Radiofrequency ablation combined with intrahepatic arterial chemoembolization in the treatment of liver cancer has definite curative effect and long-term effect.