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目的:对复方黄柏地榆紫草霜的制备以及临床疗效进行研究。方法:使用以水包油乳膏基质为制药成分进行配制,然后对复方黄柏地榆紫草霜药物进行皮肤刺激性实验和稳定性实验,再使用对比的方法验证临床疗效。最后对所获取的数据进行方差分析t检验。结果:经过稳定性实验和皮肤刺激性实验观察,配制的黄柏地榆紫草霜稳定性较好,对皮肤没有刺激性。对派瑞松霜和复方黄柏地榆紫草霜进行比较,两者比较无显著性差异(p>0.05)。结论:复方黄柏地榆紫草霜配制方便简单,质量稳定,可靠,临床疗效较好,是治疗婴幼儿湿疹的理想药霜。
OBJECTIVE: To study the preparation and clinical efficacy of Lithospermum officinale. Methods: The oil-in-water cream matrix was used as the pharmaceutical ingredient to make the skin irritation and stability test of Compound Cork elm shrub drug, and then the clinical efficacy was verified by contrast method. Finally, the data obtained were analyzed by ANOVA t-test. Results: After the stability test and skin irritation test, the Cortex Phellodendri Cortex Herba Rhizoma has better stability and no skin irritation. There was no significant difference between the two groups (p> 0.05). Conclusion: The compound Cortex Phellodendri Lithospermum is convenient and simple to prepare, stable and reliable in quality, and has good clinical curative effect. It is an ideal drug cream for the treatment of infantile eczema.