论文部分内容阅读
在印度阿育吠陀传统医学中,南非醉茄Withania somnifera Dun.是滋补强壮药,用于防治多种疾病,被称作“印度人参”。该植物中的醉茄素 A 和醉茄内酯 D 具免疫抑制活性。作者研究了该植物根70%乙醇提取物的活性部位 B(BF)的抗应激活性。该植物根阴干后磨成粗粉,用70%乙醇渗漉提取10次,提取物再用水提取5次,得到水溶部分,该部位继续分离得4个不含醉茄内酯的次级部位,将次级部位进行耐缺氧和游泳等应激试验,得到活性最强的部位BF,用 BF 进一步作以下研究:对小鼠缺氧时间和游泳时间的影响、对游泳诱导的大鼠胃溃疡的作用、对制动诱导的大鼠胃溃疡的
In Indian Ayurveda Traditional Medicine, Ashwagandha withania somnifera Dun. is a nourishing and potent medicine used to prevent and treat various diseases. It is called “Indian ginseng”. This plant has the immunosuppressive activity of alisinone A and esculin D. The authors studied the anti-stress activity of the active site B (BF) of the root 70% ethanol extract. The roots of the plant were dried and ground into coarse powder, extracted with 70% ethanol and extracted 10 times. The extract was extracted with water again for 5 times to obtain a water-soluble part. This part was further separated to obtain 4 secondary parts without ghrelisolides. The secondary site was subjected to stress tests such as hypoxia tolerance and swimming to obtain the most active site BF. The following studies were further performed using BF: effects on mouse hypoxia time and swimming time, and swimming-induced gastric ulcer in rats The effect of brake-induced gastric ulcer in rats