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庆大霉素是临床常用的氨基甙类抗生素。有关其对肾脏的损害时有报道,而引起过敏性休克者较罕见。笔者抢救成功1例庆大霉素致过敏性休克患者,现报告如下:患者男,37岁。1991年7月16日因右腿膝关节下方摔伤来换药室包扎。用生理盐水冲冼,清创。为预防感染,包扎时用庆大霉素24万单位浸湿敷料伤口局部外敷。2分钟后突然出现头晕、冷汗、胸闷、呼吸困难、四肢厥冷,倒在换药台上。查体:表情淡漠,脉搏细弱110次/分,呼吸26次/分,血压9.3/6 kPa,口唇轻度紫绀,皮肤湿冷;双肺呼吸音粗;心率110次/分,音低钝,律整。考虑是庆大霉素致过敏性休克。立刻将庆大霉素敷料去掉,用生理盐水冲洗,同时给予吸氧,肌注肾上腺素
Gentamicin is a clinically used aminoglycoside antibiotics. There are reports of damage to the kidneys, while those who cause anaphylactic shock are rare. The successful rescue of 1 case of gentamicin-induced anaphylactic shock patients are reported as follows: Male patient, 37 years old. July 16, 1991 due to fall below the right knee knee dressing room dressing. Wash with saline, debridement. To prevent infection, dressing with gentamicin 240,000 units soaked wound dressing topical. 2 minutes after a sudden dizziness, cold sweat, chest tightness, difficulty breathing, extremities Jueleng, fell on the dressing station. Physical examination: apathy, weak pulse 110 beats / min, breathing 26 beats / min, blood pressure 9.3 / 6 kPa, lips mild cyanosis, skin wet and cold; breath sounds coarse lung; heart rate 110 beats / min, whole. Consider gentamicin-induced anaphylactic shock. Gentamycin dressing immediately removed, rinsed with saline, while giving oxygen, intramuscular injection of epinephrine