,Phosphatidic Acid Regulates BZR1 Activity and Brassinosteroid Signal of Arabidopsis

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Dear Editor,Brassinosteroid (BR) is an important hormone and plays crucial roles in plant growth and development (Kim and Wang,2010).Genetics studies identify many components involving in BR signaling,including transcript factor BZR1 (BRASSINAZOLE RESISTANT 1).BZR1 is dephosphorylated (He et al.,2005) to regulate expression of target genes.A single amino acid mutation in BZR1 PEST domain results in enhanced binding and dephosphorylation by PP2A (PROTEIN PHOSPHATASE 2A;Tang et al.,2011),leading to constitutively activated BZR1 and enhanced BR signal in gain-of-function mutant bzr1-1D.Although BR signal is well characterized in Arabidopsis,how the components of BR signaling transduction pathway are regulated needs further illustrations.
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