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我们用酶免疫法检测了68例各型病毒性肝炎患者的IgE-抗HBc和总IgE。慢性乙肝中IgE-抗HBc的检出率和水平均显著高于急性乙肝。急性乙肝IgE-抗HBc的出现为一过性,持续阳性提示有慢性化趋势。HBsAg阴性的甲肝患者,IgE-抗HBc检测均为阴性。在HBsAg阳性肝炎中,51.7%的患者同时有IgE-抗HBc阳性和总IgE的增高。IgE-抗HBc是总抗HBc的一部分。IgE-抗HBc的检出说明HBV感染可诱生特异性的IgE,可能是总IgE增高的原因之一。
We used enzyme immunoassay to detect IgE-anti-HBc and total IgE in 68 patients with various types of viral hepatitis. The detection rate and level of IgE-anti-HBc in chronic hepatitis B were significantly higher than that of acute hepatitis B. The occurrence of acute hepatitis B IgE-anti-HBc is a transient, persistent positive prompts the trend of chronic. HBsAg-negative patients with hepatitis A, IgE-anti-HBc test were negative. In HBsAg-positive hepatitis, 51.7% of patients had both IgE-anti-HBc-positive and total IgE. IgE-anti-HBc is part of the total anti-HBc. Detection of IgE-anti-HBc indicates that HBV infection can induce specific IgE, which may be one of the reasons for the increased total IgE.