论文部分内容阅读
目的：观察γ－刀联合淋巴因子激活杀伤细胞（ｌｙｍｐｈｏｋｉｎｅ－ａｃｔｉｖａｔｅｄｋｉｌｉｎｇｃｅｌｓ，ＬＡＫ细胞）治疗脉络膜黑色素瘤（ｃｈｏｒｏｉｄｍａｌｉｇｎａｎｔｍｅｌａｎｏｍａ，ＣＭＭ）的效果。方法：对５例ＣＭＭ患者在ＭＲＩ定位下进行多个放射中心联合照射，另外用ＬＡＫ细胞球后注射。通过眼底、影像学及淋巴细胞亚群等检查，进行６～２４个月随访。结果：瘤体变性、萎缩、完全消退者４例，其中治疗２年后者２例，２０、１４个月者各１例。瘤体缩小３／５左右，瘤区内的血流不显示的部分消退者１例，为治疗６个月以内者。所有病例未见明显并发症。结论：本疗法治疗ＣＭＭ具有疗程较短、副反应轻、疗效较为满意等优点，是保留眼球治疗ＣＭＭ的有效方法。
Objective: To observe the effect of γ-knife combined with lymphokine-activatedkilingcels (LAK) on choroidal malignant melanoma (CMM). Methods: In 5 CMM patients undergoing MRI localization, multiple radiotherapy centers were combined and irradiated with LAK cells. Through the fundus, imaging and lymphocyte subsets and other tests, for 6 to 24 months follow-up. Results: 4 cases of degeneration, atrophy and complete remission of the tumor, 2 cases after 2 years of treatment, 1 case of 20,14 months. Tumor reduction of about 3/5, tumor area within the blood flow does not show some of the retarded in 1 case, for the treatment of less than 6 months. No obvious complications were found in all cases. Conclusion: The treatment of CMM with short course of treatment, side effects of light, more satisfied with the efficacy and so on, is to retain the eye CMM effective method.