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本文报导作者近6年来所见12例急性狼疮肺炎病例,患者年龄在15岁和65岁之间。其中7例为女性。所有患者均符合美国风湿病协会提出的系统性红斑狼疮(SLE)的诊断标准。在其中6例患者中,急性狼疮肺炎是SLE的最初表现。急性狼疮肺炎的特征是严重呼吸困难,发热,无寒颤,呼吸急促,心动过速和紫绀。7例患者伴有胸膜渗液,2例有心包炎。全部病例均有动脉血缺氧(PO_2为20～62毫米汞柱)。咽喉部、痰液和血液培养均无细菌,病毒或霉菌感染的证据。X线发现为葡萄状阴影,恒见于下叶,9例为两侧性。所有患者都用强的松(60～200毫克/日)治疗。
This article reports 12 cases of acute lupus pneumonia seen by authors in the past 6 years, with patients aged 15 and 65 years. Seven of them were women. All patients were in line with the American College of Rheumatology proposed diagnostic criteria for systemic lupus erythematosus (SLE). In 6 of these patients, acute lupus pneumonitis was the initial manifestation of SLE. Acute lupus pneumonia is characterized by severe dyspnea, fever, chills, shortness of breath, tachycardia and cyanosis. Seven patients had pleural effusion, and two had pericarditis. Arterial hypoxia (PO_2 20-62 mm Hg) was observed in all cases. No evidence of bacterial, viral or fungal infections was found in the throat, sputum and blood cultures. X-ray was found as grape-like shadows, seen in the lower lobe, 9 cases of bilateral. All patients were treated with prednisone (60-200 mg / day).