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目的探讨C反应蛋白(CRP)水平对孤立性心房颤动患者转复窦性心律后复发的预测作用。方法选取孤立性持续性房颤经药物复律或电复律患者,按其1个月内复发情况分为复发组(15例)和窦律组(18例),复律前抽取静脉血检测其CRP水平,并取18名正常人作对照。结果两组房颤患者年龄、性别、房颤持续时间、电复律的比例及左室射血分数差异均无统计学意义,但复发组左房内径明显大于窦性心律者(P<0.05)。复发组CRP水平较窦性组明显升高(P<0.05),两组CRP均比正常组显著升高(P<0.01)。结论孤立性房颤患者复律前CRP水平可作为复律后复发的预测指标。
Objective To investigate the predictive value of C-reactive protein (CRP) levels in the recovery of sinus rhythm after recurrent atrial fibrillation in patients with atrial fibrillation. Methods Patients with isolated persistent AF undergoing drug cardioversion or electrical cardioversion were divided into recurrent group (n = 15) and sinus rhythm group (n = 18) according to the recurrence within one month. Venous blood samples were collected before cardioversion The CRP level, and take 18 normal controls. Results There was no significant difference in age, sex, duration of AF, electrical cardioversion and left ventricular ejection fraction in two groups of patients with atrial fibrillation. However, the left atrial diameter was significantly larger in patients with recurrence than in sinus rhythm (P <0.05) . The level of CRP in recurrence group was significantly higher than that in sinusitis group (P <0.05), CRP in both groups was significantly higher than that in normal group (P <0.01). Conclusion The level of pre-rupture CRP in patients with isolated atrial fibrillation can be used as a predictor of recurrence after cardioversion.