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目的 观察分析传染性非典型肺炎 (SARS)患者血细胞形态学变化。方法 2 2 0例临床确诊的SARS患者 (包括死亡病例 )、2 0例细菌性肺炎和 2 0例病毒性肺炎患者外周血涂片 ,经瑞氏染色后 ,用普通光学显微镜观察其细胞形态。结果 SARS患者血细胞形态发生了明显的变化 ,其中1 6 7例患者中性粒细胞细胞核表面出现鼓槌样结构 ,1 5 6例的患者中性粒细胞质中非特异性颗粒粗大 ,1 2 1例的患者中性粒细胞出现空泡变性。其他肺炎患者血细胞未见上述形态学的改变。结论 中性粒细胞核鼓槌样形成可能与SARS病程有关
Objective To analyze the changes of hemocyte morphology in patients with SARS. Methods Twenty-two cases of SARS patients (including deaths), 20 cases of bacterial pneumonia and 20 cases of viral pneumonia were smeared by Wright’s stain, and their cell morphology was observed by ordinary light microscope. Results The morphology of blood cells in SARS patients changed significantly. Among them, drumstick-like structures appeared on the surface of the neutrophil nuclei in 167 patients, while the nonspecific granules in the neutrophilic cytoplasm of 165 patients were thick. Among them, 121 Patients with neutrophil vacuolar degeneration. Other pneumonia patients did not see the above morphological changes in blood cells. Conclusion Neutrophil nuclear drumstick-like formation may be related to the course of SARS