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越来越多的实验证据表明凋亡与肿瘤发展中血管生成有关。为了探索肿瘤细胞自发性凋亡与肿瘤内血管生成如何相关,作者在101例胃癌病人中用凋亡标记药盒法(ApopTeqKit)测定凋亡指数,并用抗CD34单克隆抗体测定肿瘤内微血管密度。同时作免疫组化染色测Ki—67标记指数及P53基因
More and more experimental evidence indicates that apoptosis is related to angiogenesis in tumor development. In order to explore the relationship between spontaneous apoptosis of tumor cells and tumor angiogenesis, the authors determined apoptosis index in 101 patients with gastric cancer by ApopTeqKit and determined the microvessel density in tumors using anti-CD34 monoclonal antibody. Simultaneous immunohistochemical staining for Ki-67 marker index and P53 gene