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本文检测５０例乙型肝炎后肝硬化患者腹水和血清中白细胞介素６（ＩＬ－６）、肿瘤坏死因子α（ＴＮＦα）的含量。结果显示：血清和腹水ＩＬ－６、ＴＮＦ－α水平均显著高于正常（Ｐ＜０．０５或０．０１）。腹水感染者血清和腹水ＩＬ－６、ＴＮＦα水平高于非感染者（Ｐ＜０．０１或０．００１），当感染控制后血清和腹水ＩＬ－６、ＴＮＦα水平仅能降至非感染者水平而不能恢复正常。结果揭示，ＩＬ６、ＴＮＦα参与肝炎后肝硬化病理发展过程并在腹水的形成中发挥作用。检测血清和腹水ＩＬ６、ＴＮＦα值变化对肝硬化腹水合并腹腔感染的诊断、判断疗效具有一定指导意义
In this paper, the levels of interleukin 6 (IL-6) and tumor necrosis factor α (TNFα) in ascites and serum of 50 cirrhotic patients with hepatitis B were detected. The results showed that the serum and ascites IL-6, TNF-α levels were significantly higher than normal (P <0.05 or 0.01). The levels of IL-6 and TNFα in serum and ascites of patients with ascites infection were significantly higher than those of non-infected patients (P <0.01 or 0.001). After infection control, the levels of IL-6 and TNFα in serum and ascites were only decreased to non-infected patients And can not be restored to normal. The results revealed that IL6, TNFα participate in the pathogenesis of posthepatitic cirrhosis and play a role in the formation of ascites. Detection of serum and ascites IL6, TNFα changes in cirrhotic patients with ascites and abdominal infection diagnosis, to determine the efficacy of a certain guiding significance