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红细胞电泳时间(EPT)是反映红细胞表面电荷密度的一项重要指标,EPT延长,红细胞易于聚集,可致全血粘度升高、微循环障碍。心肺复苏(CPR)后, EPT的变化目前尚未见报道。本实验通过对新西兰兔心脏骤停模型的研究,探讨了CPR后EPT变化及肝素治疗对其影响。结果显示:CPR后EPT明显延长(P<0.01),尤以 CPR后 10分钟明显,以后逐渐恢复;复苏后早期肝素治疗可使 CPR后延长的 EPT改善.结论: CPR后EPT明显延长,早期肝素治疗可使其改善。
Erythrocyte electrophoresis time (EPT) is an important indicator of erythrocyte surface charge density. EPT is prolonged, erythrocytes are easy to accumulate, which can cause whole blood viscosity and microcirculation. After CPR, the change of EPT has not been reported yet. This experiment through the New Zealand rabbit cardiac arrest model to explore the change of EPT after CPR and the impact of heparin therapy. The results showed that EPT was significantly prolonged after CPR (P <0.01), especially at 10 minutes after CPR, and gradually recovered after CPR. The treatment with early heparin after CPR improved EPT prolonged after CPR. Conclusion: After EPR EPT significantly prolonged, early heparin therapy can make it improve.