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目的探讨米非司酮配伍利凡诺(依沙吖啶)终止中期妊娠的治疗效果。方法将80例孕14～27周要求终止妊娠的健康妇女,随机分为观察组40例(米非司酮配伍利凡诺),对照组40例(单用羊膜腔穿刺注入利凡诺)。观察二组宫腔给药至宫缩发动时间,宫缩至胎盘排出时间、产后出血量,胎盘胎膜残留情况。结果观察组宫腔给药至宫缩发动时间,宫缩至胎盘排出时间、产后出血量,胎盘胎膜残留情况均少于对照组,差异有统计学意义。结论采用米非司酮配伍利凡诺引产可以缩短产程,减少胎盘胎膜残留,减少产后出血,值得临床推广使用。
Objective To investigate the efficacy of mifepristone combined with rivanol (ethacridine) in the termination of mid-term pregnancy. Methods Eighty healthy pregnant women who required termination of pregnancy from 14 to 27 weeks of gestation were randomly divided into observation group of 40 cases (mifepristone with rivanol) and control group of 40 cases (rifamycin alone amniocentesis). Observe the two groups intrauterine administration of uterine contractions to start the time, contractions to the placenta discharge time, postpartum hemorrhage, placental fetal membrane residue. Results The intrauterine administration of the observation group to the time of uterine contractions, uterine contractions to the placenta discharge time, postpartum hemorrhage, placental fetal membrane residue were less than the control group, the difference was statistically significant. Conclusion Adopting mifepristone and rivanol to induce labor can shorten the labor process, reduce the residual of fetal membranes and reduce the postpartum hemorrhage. It is worth to be used clinically.