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维持血透的尿毒症患者常可见骨外钙沉积。许多部位的软组织包括血管、内脏、主动脉周围均可见局部钙化。本文首次报道1例血透患者发生颌下腺钙化。患者34岁,黑人妇女。因系统性红斑狼疮(SLE)伴终末期肾衰作维持血透,每周透析3次,每次3h已2年。患者主诉双侧颌下腺肿痛,无其他唾液腺受累和干燥综合征的临床表现。X线检查发现两侧颌下腺大量钙化,其他唾液腺未被累及。此外,右髋部有一个小的软组织钙化灶。无纤维性骨炎和其他骨病的X线征象。血生化检查总钙正常(2.4mmol/L),磷酸盐增高(2.0～3.8mmol/L),钙磷乘积升高。血碱性磷酸酶活性和25-羟维生素D浓度正常。去铁敏试验阳性(即注射60mg/kg去铁敏后24h血铝自2.9μmol/L上升至9.2μmol/L)。应用磷结合剂、限制饮食中磷
Urticaria to maintain hemodialysis patients often see extraosteal calcium deposition. Many parts of the soft tissue, including blood vessels, visceral, local aortic calcification can be seen around. This article first reported 1 case of hemodialysis patients with submandibular calcification. Patient 34 years old, black woman. Due to systemic lupus erythematosus (SLE) with end-stage renal failure to maintain hemodialysis, dialysis 3 times a week, each 3h 2 years. Patients complained of bilateral submandibular gland swelling and pain, and no other salivary gland involvement and clinical manifestations of Sjögren’s syndrome. X-ray examination found that both sides of the submandibular gland calcification, other salivary glands have not been involved. In addition, there is a small soft tissue calcification in the right hip. No fibrous osteitis and other bone diseases X-ray signs. Blood biochemical examination of normal calcium (2.4mmol / L), phosphate increased (2.0 ~ 3.8mmol / L), calcium and phosphorus products increased. Blood alkaline phosphatase activity and 25-hydroxy vitamin D concentrations were normal. Deferoxamine test positive (ie, injection of 60mg / kg deferoxamine 24 hours after the blood aluminum from 2.9μmol / L increased to 9.2μmol / L). Use a phosphate binder to limit dietary phosphorus