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目的探讨口服黄体酮胶囊治疗青春期功能失调性子宫出血患者的临床疗效。方法选取我院2013年1月至2014年1月收治的青春期功血患者110例,随机将其分为对照组与观察组各55例,对照组患者给予黄体酮注射液开展贯序疗法治疗,观察组患者给予黄体酮胶囊开展贯序疗法治疗,观察两组患者的月经改善与不良反应情况,并进行比较与分析。结果治疗结束后,两组患者月经情况均有明显改善,但月经改善程度与不良反应发生率组间比较差异无统计学意义(P>0.05)。结论应用黄体酮胶囊口服治疗青春期功血患者与黄体酮注射液肌内注射的有效性和安全性相当,均可明显改善患者的月经情况,但胶囊制剂的给药方式更简单,具有较好的经济效益。
Objective To investigate the clinical efficacy of oral progesterone capsules in the treatment of adolescent dysfunctional uterine bleeding. Methods One hundred and ten patients with adolescent dysfunctional uterine bleeding admitted to our hospital from January 2013 to January 2014 were randomly divided into control group and observation group with 55 cases each. Patients in the control group were treated with progesterone injection for sequential therapy, Patients in the observation group were treated with sequential therapy of progesterone capsules, menstrual improvement and adverse reactions were observed in two groups of patients, and compared and analyzed. Results After the treatment, both groups had significant improvement of menstruation, but there was no significant difference between the two groups in the improvement of menstruation and the incidence of adverse reactions (P> 0.05). Conclusions The efficacy and safety of intradermal injection of progesterone capsules in patients with adolescent dysfunctional uterine bleeding during the treatment of adolescent dysfunctional uterine bleeding are similar, which can significantly improve the menstrual status of patients. However, the administration mode of capsule preparation is simple and has good Economic benefits.