LMP2-DC Vaccine Elicits Specific EBV-LMP2 Response to Effectively Improve Immunotherapy in Patients

• 作 者: ZENG Yi SI Yong Feng LAN Gui P
• 机 构: StateKeyLaboratoryforInfectiousDiseasePreventionandControl,People',sHospitalofGuangxiZhuangAutono
• 出 处: 生物医学与环境科学:英文版
• 发表日期: 2020年11期
• 关键词: LMP2-DCs Nasopharyngeal carcinoma IMMUNOTHERAPY
• 基金项目: Mega Project of Research on the Prevention and Control of HIV/AIDS,Viral Hepatitis Infectious Diseases[Grant No:2018ZX10102001],the Key Science and Technology Program of Guangxi Zhuang Autonomous Regi

Objective To evaluate the safety and effectiveness of a vaccine based on latent membrane protein 2(LMP2)modified dendritic cells(DCs)that boosts specific responses of cytotoxic T lymphocytes(CTLs)to LMP2 before and after intradermal injection in patients