论文部分内容阅读
报道５２例正常人、３３例肺癌、１９例肺结核、１４例肺心病、１２例慢性阻塞性肺病（ＣＯＰＤ）患者的血清血管紧张素转换酶（ＳＡＣＥ）活性水平，同时测定１２例癌性胸水和１０例结核性胸水患者胸水中ＡＣＥ（ＰＡＣＥ）及其与ＳＡＣＥ比值。结果表明，肺癌、肺心病及ＣＯＰＤ组ＳＡＣＥ活性均低于正常组（Ｐ＜０．０１）；肺结核组ＳＡＣＥ活性与正常组无明显差异（Ｐ＞０．０５）。癌性胸水患者ＰＡＣＥ／ＳＡＣＥ比值低于结核性胸水患者（Ｐ＜０．００１）。提示ＳＡＣＥ活性及ＰＡＣＥ／ＳＡＣＥ比值测定，对肺部疾病及胸水定性有一定的鉴别诊断意义
52 cases of normal, 33 cases of lung cancer, 19 cases of pulmonary tuberculosis, 14 cases of pulmonary heart disease, 12 cases of chronic obstructive pulmonary disease (COPD) in patients with serum levels of angiotensin-converting enzyme (SACE), simultaneous determination of 12 cases of cancerous pleural effusion and The pleural fluid ACE (PACE) and its ratio to SACE in 10 patients with tuberculous pleural effusion. The results showed that SACE activity in lung cancer, pulmonary heart disease and COPD group was lower than that in normal group (P <0.01). SACE activity in pulmonary tuberculosis group was not significantly different from that in normal group (P> 0.05). Patients with cancerous pleural effusion had a lower PACE / SACE ratio than patients with tuberculous pleural effusion (P <0.001). Prompt SACE activity and PACE / SACE ratio determination of pulmonary disease and pleural effusion have some differential diagnosis of diagnostic significance