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目的探讨肠内营养在重症急性胰腺炎(SAP)治疗中的应用价值。方法分析30例SAP患者的临床资料,按营养支持不同分为肠内营养(EN)16例和全胃肠外营养(TPN)14例。观察两组治疗结果及临床指标的变化。结果营养支持2周后,两组患者的APACHEⅡ评分、CTSI较前显著降低,且EN组的各项评分均显著低于TPN组,差异均有高度统计学意义(均P<0.01)。营养支持后两组的血糖、血清白蛋白、血钙和血肌酐均较前有显著改善,差异有高度统计学意义(P<0.01),但两组之间各项指标的差异无统计学意义(P>0.05)。同时,EN组平均住院天数明显缩短,中转手术率、感染率、病死率方面EN组均明显低于TPN组,差异均有统计学意义(均P<0.05)。结论EN治疗SAP疗效优于TPN,应用于临床是安全可行的。
Objective To investigate the value of enteral nutrition in the treatment of severe acute pancreatitis (SAP). Methods The clinical data of 30 patients with SAP were analyzed and divided into 16 cases of enteral nutrition (EN) and 14 cases of total parenteral nutrition (TPN) according to nutritional support. Observation of the two groups of treatment results and clinical indicators of change. Results After 2 weeks of nutritional support, the APACHEⅡscore and CTSI of the two groups were significantly lower than before, and the scores of EN group were significantly lower than those of TPN group (all P <0.01). The blood sugar, serum albumin, serum calcium and serum creatinine of the two groups were significantly improved after the nutritional support, the difference was highly statistically significant (P <0.01), but there was no significant difference between the two groups (P> 0.05). At the same time, the average length of stay in EN group was significantly shortened. The EN group in the EN group was significantly lower than the TPN group in the rate of operation, infection, and mortality (all P <0.05). Conclusions EN is superior to TPN in the treatment of SAP, which is safe and feasible for clinical application.