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1 临床资料患者男性,25岁,主因意识丧失2次,心跳、呼吸骤停15min,于2005年5月8日11:45时入院。患者1周前患股癣,遵医嘱服酮康唑(Ketoconazole)200 mg(西安杨森制药有限公司),每日2次,连服7d 后,加用特非那定(Terfenadine)60mg(江苏联环药业股份有限公司),每日2次。翌日(5月8日)上午10时许,患者突然昏倒,呼之不应,未行处理,5min后自行清醒,未引起重视,继续干活。1h 后再次出现意识丧失,四肢抽搐,小便失禁,呼吸、心跳停止,即送我院急诊科。患者无慢性病史。查体:意识丧失,面色青紫,无呼吸,无心音,心电图呈直线,双侧瞳孔散大,对光反射消失,生理反射消失,病理反射未引出。立即心脏按压,电击除颤,气管插管,呼吸机控制呼吸,静脉注射肾上腺素、阿托品、利多卡因、
1 clinical data Male patients, 25 years old, the main loss of consciousness 2 times, heart rate, respiratory arrest 15min, at 0545 on May 8, 2005 at admission. Patients suffered from ringworm one week ago, prescribed ketoconazole 200 mg twice daily (Xi’an Janssen Pharmaceutical Co., Ltd.) twice a day for 7 days and treated with Terfenadine 60 mg Central Pharmaceutical Co., Ltd.), 2 times a day. The next day (May 8) at 10 am, the patient suddenly collapsed, call should not, did not deal with, 5min after their own sober, did not pay attention to continue to work. After 1h again loss of consciousness, limbs twitch, urinary incontinence, breathing, cardiac arrest, that is sent to our hospital emergency department. No history of chronic disease. Physical examination: loss of consciousness, looking bruising, no breathing, no heart sound, ECG was linear, bilateral mydriasis, light reflex disappeared, physiological reflex disappeared, pathological reflex did not lead. Immediate cardiac compression, defibrillation, endotracheal intubation, ventilator controlled breathing, intravenous epinephrine, atropine, lidocaine,