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氟卡胺为 IC 类抗心律失常药,作者分析了对至少超过1天而短于半年的房颤患者给予氟卡胺转复为窦律的作用.方法:研究69例(男44,女25),平均年龄63±14岁,在研究前停所有抗心律失常药、地高辛及钙拮抗剂.全部病例都有短于半年的房颤.口服后,进行心电图、超声心动图、胸片检查及心电监护.氟卡胺稀释在5%糖水中首次推注50mg(10分钟以上),如未复律,20分钟后再给第2次,直到最大量达2mg/kg。注射期间每2分钟测一次血压。静注之后改为口服氟卡胺,体重在50kg 内为200mg/日,70kg 以上为300mg/日.其间记录心电图及询问副作用,恢复为窦律便结束研究.如房颤持续2天以上或需电复律者则认为无效。
Flecainide is an IC antiarrhythmic drug, the authors analyzed the effect of flecainide on sinus rhythm in patients with AF for at least more than 1 day and less than 6 months.Methods: 69 patients (male 44, female 25 ), Mean age 63 ± 14 years, stopping all anti-arrhythmic drugs, digoxin and calcium antagonists prior to the study. All cases had atrial fibrillation for less than six months. After oral administration, ECG, echocardiography, Check-up and ECG monitoring. Flecainide Dilution First push 50 mg (10 minutes or more) in 5% sugar water, if no cardioversion, give 2nd after 20 minutes until maximum 2 mg / kg. Blood pressure was measured every 2 minutes during the injection. Intravenous flecainide, weight within 50kg 200mg / day, 70kg above 300mg / day during recording ECG and ask side effects, return to the sinus rhythm will end the study, such as atrial fibrillation for more than 2 days or on demand Cardioversion is considered invalid.