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目的探讨老年慢性阻塞性肺疾病(COPD)合并呼吸衰竭治疗中无创机械通气的应用效果。方法 136例COPD合并呼吸衰竭老年患者,随机分为对照组及观察组,各68例。对照组采用常规治疗,观察组在对照组基础上给予无创机械通气治疗,比较两组的临床疗效。结果观察组的治疗总有效率、动脉氧分压(Pa O2)、动脉二氧化碳分压(Pa CO2)、呼吸频率、心率等指标均明显优于对照组,比较差异均有统计学意义(P<0.05)。结论应用无创机械通气治疗老年COPD合并呼吸衰竭,其临床疗效确切,且操作简单,早期应用可促进疾病康复,对提高患者生活质量具有积极意义,值得临床推广应用。
Objective To investigate the effect of noninvasive mechanical ventilation in the treatment of senile chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Methods 136 elderly COPD patients with respiratory failure were randomly divided into control group and observation group, with 68 cases in each group. The control group received routine treatment. The observation group received non-invasive mechanical ventilation on the basis of the control group, and the clinical efficacy was compared between the two groups. Results The total effective rate, Pa O2, Pa CO2, respiration rate and heart rate in observation group were significantly better than those in control group (P < 0.05). Conclusion The application of non-invasive mechanical ventilation in the treatment of elderly patients with COPD and respiratory failure has definite curative effect and simple operation. Early application can promote the rehabilitation of the disease and has positive significance for improving the quality of life of patients, which is worthy of clinical application.