杜塞酰胺导致未手术眼的脉络膜脱离

• 作 者: 李晶明g Sa S Blumenthal E.Z
• 机 构: Department of Oph-thalmolog y,Hadassah-Hebrew Univ.Medical Cen-ter,Jerusalem,Israel.Dr.
• 出 处: 世界核心医学期刊文摘.眼科学分册
• 发表日期: 2005年01期
• 关键词: 脉络膜脱离 降眼压药物 手术 激素滴眼液 碳酸酐酶抑制剂 超声检查 眼科手术 观察性 并发症 病例

Purpose Choroidal detachment is a known complication of topical hypotensive agents when use d to treat eyes sensi-tized by prior surgery.We document t he abrupt develop-ment of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with pri-mary open-angle glaucoma.Design Observational case re-port.Methods A 76-year-old woman wi th primary open-angle glaucoma and no history o f ocular surgery de-veloped a choroidal detachment 12hours after initiation of therapy with dorzolamide eye drops.Choroidal detachment was diagnosed clinically and confir med by echography.Results Withdrawal of the drug and in itiation of corticos-teroid drops resulted in prompt reso lution of the choroidal detachment.Conclusions Choroidal detachment can occur in surgically untreated eyes after u se of a topical carbonic anhydrase inhibitor.

Purpose Choroidal detachment is a known complication of topical hypotensive agents when use d to treat eyes sensi-tized by prior surgery. We document t he abrupt develop-ment of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with pri- mary open-angle glaucoma. Design Observational case re-port. Methods A 76-year-old woman wi th primary open-angle glaucoma and no history of ocular surgery de-veloped a choroidal detachment 12hours after initiation of therapy with dorzolamide eye drops. Choroidal detachment was diagnosed clinically and confirmed by echography. Results Withdrawal of the drug and iniation of corticos-teroid drops resulted in prompt reso lution of the choroidal detachment. Conclusions Choroidal detachment can occur in surgically untreated eyes after u se of a topical carbonic anhydrase inhibitor.