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自从70年代早期第一个有关日蛋白毫微球的报道问世以来,这些可生物降解并具生物相容性的微粒被发现可应用于许多方面。本研究采用一种以乳化交联为基础的制备方法,因为采用此方法可使水溶性的治疗和诊断剂有效地包入白蛋白微球中。此外,正交中间组分设计被用于评价五个重要?
These biodegradable and biocompatible microparticles have been found to be applicable in many aspects since the first report on the albumin nanosphere in the early 1970s. In this study, a preparation based on emulsion cross-linking was used because water-soluble therapeutic and diagnostic agents were effectively encapsulated in albumin microspheres using this method. In addition, orthogonal middle component design is used to evaluate five important?