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目的 为了解长期维持性血液透析患者丙型肝炎病毒 (HCV)感染与血液透析、输血之间的关系。方法 对 2 2例维持性血液透析患者于透析前、透析后定期测抗HCV抗体、肝功能。结果 透析前 2例抗HCV抗体阳性 ,透析 1、2、3年抗HCV抗体累积阳性率分别为 2 7.3 %、36 .4%、40 .9%。输血 >6次及输血量 >10 0 0ml,抗HCV抗体阳性率为 77.8%、80 .0 % ,9例抗HCV抗体阳性患者无任何临床表现 ,仅 5例ALT >5 0U/L。结论 维持性血液透析患者HCV感染与输血次数、输血量及透析时间有关 ,使用促红细胞生成素改善慢性肾功能衰竭患者的贫血 ,减少输血 ,可减少HCV感染
Objective To understand the relationship between hepatitis C virus (HCV) infection and hemodialysis and blood transfusion in long-term maintenance hemodialysis patients. Methods 22 cases of maintenance hemodialysis patients before dialysis, anti-HCV antibody and liver function after dialysis regularly. Results The positive rates of anti-HCV antibodies in 2 cases before dialysis were 23.3%, 36.4% and 40.9%, respectively, at 1, 2 and 3 years after dialysis. The blood transfusions> 6 times and blood transfusion> 10 0ml, the positive rate of anti-HCV antibody was 77.8%, 80.0%. There were no clinical manifestations in 9 anti-HCV antibody positive patients. Only 5 ALT> 50U / L. Conclusions HCV infection in maintenance hemodialysis patients is related to the number of blood transfusions, blood transfusion and dialysis time. Erythropoietin is used to improve anemia, reduce blood transfusion and reduce HCV infection in patients with chronic renal failure