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目的:本研究通过将唐传(厦门)生物科技有限公司生产的L-阿拉伯采用口服方法,喂服新西兰大白兔,同时用高糖高脂饲料喂养兔子,观察L-阿拉伯糖对抑制因为连续高糖高脂饲料引起的血脂紊乱和脂肪堆中的作用。为将L-阿拉伯糖应用到预防肥胖以及由此引发的并发症提供科学数据。方法:择体重在1.8～2.0kg范围新西兰大白兔32只,随机分为A,B,C组,每组8,其中A～C组均喂养高糖高脂饲料,D组喂普通饲料,同时A组按1.24g/d,B组按1.11g/d剂量口服L-阿拉伯糖进行干预。实验持续3个月,实验结束,颈动脉取血扑杀兔子,分离血清采用贝克曼全自动生化仪检测血脂水平,包括总胆固醇(TC),甘油三脂(TG)水平,同时分离腹部脂肪和肾脏周围脂肪,称重并计算脂肪指数。结果:生化指标检测结果显示,口服L-阿拉伯糖高剂量组的兔子TG水平比对照组低,差异显著(P<0.05),TC水平比对照组低17%,但没有达到显著性差异,脂肪指数结果证明,两个剂量组的兔子脂肪指数明显比实验对照组低,差异显著(P<0.05)。结论:1.24g/d剂量的L-阿拉伯糖能够有效降低胆固醇和甘油三脂水平,同时能够有效抑制兔子体内脂肪堆积,减少脂肪指数。
OBJECTIVE: In this study, New Zealand white rabbits were fed orally by L-Arabian produced by Tang Chuan (Biotechnology) Co., Ltd. while rabbits were fed with high-sugar and high-fat diet. The effect of L-arabinose on inhibition Dyslipidemia caused by high-fat diets and the role of fat fats. Provide scientific data for the application of L-arabinose to prevent obesity and the complications caused thereby. Methods: Thirty-two New Zealand white rabbits weighing 1.8-2.0kg were randomly divided into groups A, B and C, each group had 8 rats in each group. A group of 1.24g / d, B group 1.11g / d oral dose of L-arabinose intervention. The experiment lasted for 3 months. At the end of the experiment, rabbits were sacrificed by carotid blood and the blood serum was separated and the blood lipid level was measured by Beckman automatic biochemical analyzer, including total cholesterol (TC) and triglyceride (TG) Kidney fat around, weighing and calculating fat index. Results: The results of biochemical tests showed that the level of TG in rabbits fed L-arabinose high dose group was significantly lower than that in control group (P <0.05), TC level was 17% lower than that in control group, but the difference was not significant The index results showed that the rabbits fat index of the two dose groups was significantly lower than the experimental control group (P <0.05). Conclusion: 1.24g / d dose of L-arabinose can effectively reduce cholesterol and triglyceride levels, while being able to effectively inhibit rabbit body fat accumulation, reduce the fat index.