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钙化似乎是生物瓣膜自发性变性过程的一个主要因素。据报告,严重钙化的发生率各组不同,为63～79%。钙化与置入时间有关,Cipria-no等报告,置入时间少于3年的其自发变性瓣膜钙化为30%;3～5年的为82%;5年以上为96%。然而很明显,钙化虽很常见,但并不一定伴随自发变性。根据作者的观察,所有自发变性的瓣膜,其钙化紧靠撕裂或穿孔部位的占50%。在严重钙化的瓣膜中,钙盐沉积在邻近撕裂或穿孔处的为71%,这提示钙化与发生撕裂有关。另外,7%的自发变性瓣膜钙化可影响瓣膜的开
Calcification seems to be a major factor in the spontaneous degeneration of biological valves. According to the report, the incidence of severe calcification varies from group to group, ranging from 63 to 79%. Calcification and placement time, Cipria-no other reports, less than 3 years of implantation of its spontaneous degeneration valve calcification 30%; 3 ~ 5 years was 82%; 5 years 96%. However, it is clear that calcification, though common, is not necessarily accompanied by spontaneous degeneration. According to the authors’ observation, all spontaneous degenerative valves have calcifications that are close to 50% of the torn or perforated areas. In severely calcified valves, calcium deposition was 71% at adjacent tears or perforations, suggesting that calcification is associated with tearing. In addition, 7% of spontaneous degenerative valve calcifications can affect valve opening