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目的分析中国(未包括香港、澳门特别行政区和台湾地区,下同)2008~2009年新生儿破伤风(Neonatal Tetanus,NNT)的流行病学特征。方法利用描述流行病学方法分析2008~2009年NNT监测数据。结果中国2008、2009年NNT报告发病率分别为0.1/1000活产儿(‰)、0.08‰,病死率分别为10.7%、9.7%;2009年NNT发病率≥1‰的县有32个,分布于10个省(自治区),其中75%的县位于西部地区,22%位于东部地区,3%位于中部地区。2008~2009年NNT病例男女性别比分别为2.1∶1;发病日龄平均为(6±3.5)d;在家出生的病例占84%;仅有0.41%病例的母亲曾接种过破伤风疫苗(Tetanus Vaccine,TV)。结论中国2008~2009年NNT发病率已控制在<1‰,但仍存在NNT发病率≥1‰的县,应继续推行清洁接生,提高住院分娩率。
Objective To analyze the epidemiological characteristics of neonatal tetanus (Neonatal Tetanus, NNT) in China (excluding Hong Kong, Macau Special Administrative Region and Taiwan). Methods Descriptive epidemiological methods were used to analyze NNT monitoring data from 2008 to 2009. Results The incidence rates of NNT in China in 2008 and 2009 were 0.1 / 1000 live births (‰) and 0.08 ‰, respectively. The case fatality rates were 10.7% and 9.7% respectively. There were 32 counties with NNT incidence ≥1 ‰ in 2009 10 provinces (autonomous regions), of which 75% counties in the western region, 22% in the eastern region, 3% in the central region. The sex ratio of men and women in NNT cases was 2.1: 1 between 2008 and 2009 respectively. The average age of onset was (6 ± 3.5) d. The number of births at home was 84%. Only 0.41% of mothers had tetanus vaccination (Tetanus Vaccine, TV). Conclusion The incidence of NNT in China from 2008 to 2009 has been controlled at <1 ‰, but there are still counties with NNT incidence ≥1 ‰, and the follow-up of clean delivery and hospital delivery rate should be continued.