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目的探讨穿刺活检乳腺癌的临床病理特点及生物学指标在乳腺癌诊断、治疗、预后中的应用。方法收集2010年1月—2013年4月间病理确诊的76例穿刺活检的乳腺癌病例,进行回顾分析。结果 76例乳腺癌患者,发病年龄以41~50岁最多,占47.4%,肿块以外上象限最多,占51.3%,最主要的临床症状为无痛性乳腺肿块,占86.8%。病理类型以浸润性导管癌多见,占76.3%,ER、PR、C-erbB-2、CK34βE12、Ki-67阳性率分别为55.3%、52.6%、42.1%、61.8%、64.5%,P63阴性率94.7%。结论做好知识宣教,加强体检,早发现,早诊断,早治疗是预防和控制乳腺癌的关键。
Objective To investigate the clinical and pathological characteristics of biopsy breast cancer and its application in the diagnosis, treatment and prognosis of breast cancer. Methods Totally 76 cases of breast cancer biopsy were collected from January 2010 to April 2013 and retrospectively analyzed. Results 76 cases of breast cancer patients, the age of onset to 41 to 50 years of age, accounting for 47.4%, the upper quadrant outside the mass, accounting for 51.3%, the most important clinical symptoms of painless breast mass, accounting for 86.8%. The positive rate of invasive ductal carcinoma was 76.3%. The positive rates of ER, PR, C-erbB-2, CK34βE12 and Ki-67 were 55.3%, 52.6%, 42.1%, 61.8%, 64.5% Rate of 94.7%. Conclusion Good knowledge of education, strengthen physical examination, early detection, early diagnosis and early treatment is the key to prevention and control of breast cancer.